CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Unidad Ejecutora - UE
Structural and Spectroscopic Characterization of 2,2'-methylenedi-8-quinolinol dihydrochloride dihydrate
J ZINCZUK; PIRO, OE; CASTELLANO, EE; ENRIQUE JOSE BARAN
Journal of Molecular Structure
Lugar: Amsterdam/Holanda; Año: 2008 vol. 892 p. 216 - 216
The crystal structure of the title compound, a promising ligand for chelatotherapies in the treatment of Alzheimer's disease, has been determined by single crystal X-ray diffractometry. The compound crystalized in the monoclinic space group C2/c with Z = 4. The dimeric 8-quinolinol molecule is sited on a crystallographic twofold axis passing through the CH2 carbon atom that links the symmetry related molecular halves, giving rise to a two-bladed propeller-like conformation. The 1H and 13C NMR as well as the FT-IR and Raman spectra of the compound were also recorded and are briefly discussed. Some omparisons with spectra of related species are made.