On the Interaction of Vanadium Species with meso-2,3-Dimercaptosuccinic Acid

WILLIAMS, PAM; ENRIQUE JOSE BARAN

Biological Trace Element Research

Humana Press

Año: 2006 vol. 109 p. 189 - 194

0163-4984

 The interaction of the oxovanadium(IV) cation with meso-2,3-dimercaptosuccinic acid (DMSA) was investigated by electron absorption spectroscopy in aqueous solution at different pH values. The spectral behavior, complemented with a spectrophotometric titration shows the generation of a [VO(DMSA)2](2-) complex in which the oxocation interacts with two pairs of deprotonated -SH groups of the acid. It was also found that DMSA rapiodly reduces VO3(-) to VO(2+), which might be chelated by an excess of the acid. DMSA can also produce the partial reduction of V2O5 suspensions at pH = 5.2. The results of this study suggest that DMSA might be a potentially useful detoxification agent for vanadium.