CEQUINOR 05415
CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Unidad Ejecutora - UE
artículos
Título:
Bis(oxalato)dioxovanadate(V) and bis(oxalato)oxoperoxo- vanadate(V) complexes: Spectroscopic characterization and biological activity
Autor/es:
IGNACIO E. LEÓN ; SUSANA B. ETCHEVERRY; BEATRIZ S. PARAJÓN COSTA; ENRIQUE J. BARAN
Revista:
BIOLOGICAL TRACE ELEMENT RESEARCH
Editorial:
HUMANA PRESS INC
Referencias:
Lugar: Totowa, NJ; Año: 2013 vol. 155 p. 295 - 300
ISSN:
0163-4984
Resumen:
Two structurally related vanadium(V) complexes, K3[VO2(C2O4)2]·3H2O and K3[VO(O2)(C2O4)2]·1/2H2O, were thoroughly characterized by infrared, Raman, and electronic spectroscopies. The effect of both complexes on the viability of the human MG-63 osteosarcoma cells was tested using the MTTassay. The monoperoxo complex shows a very strong antiproliferative activity (at 100-μMconcentration, this complex diminished the cell viability ca. 80 %), whereas the dioxo complex was inactive.
