CEQUINOR   05415
CENTRO DE QUIMICA INORGANICA "DR. PEDRO J. AYMONINO"
Unidad Ejecutora - UE
artículos
Título:
One-pot synthesis of 2-trifluoromethylchromones
Autor/es:
ISABEL C. HENAO CASTAÑEDA; SONIA E. ULIC; CARLOS O. DELLA VÉDOVA; NILS METZLER-NOLTE ; JORGE L. JIOS
Revista:
TETRAHEDRON LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2011 vol. 52 p. 1436 - 1436
ISSN:
0040-4039
Resumen:
We report a simple and suitable method for the preparation of useful 2-tri.uoromethylchromones in one step, in high yields and avoiding the use of solvents. We were able to detect the intermediate of this reaction. Furthermore a mechanism for the formation of the 7-methoxy-3-tri.uoroacetyl-2-trifluoromethylchromone through the unexpected double tri.uoroacetylation of 4-methoxy-2-hydroxyacetophenone followed by dehydration is also proposed. All compounds are fully identifed and characterized by spectroscopic techniques.