IQUIR   05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Towards a sustainable methodology for the generation of organic libraries: The concept of amplification of molecular diversity
Autor/es:
DELPICCOLO C. M. L. ; PRADA GORI D. N.
Lugar:
Golden, Colorado, United States of America
Reunión:
Taller; 2018 ACS Summer School on Green Chemistry & Sustainable Energy; 2018
Institución organizadora:
American Chemical Society
Resumen:
One of the current challenges of organic and medicinal chemistry isthe rapid generation of libraries of complex and diverse compounds,thereby accelerating the drug discovery process. To achieve this goal,we develop a synthetic strategy in which the number and structuraldiversity of small molecules obtained is increased, combiningdiversity-oriented synthesis strategies (DOS), catalysis by transitionmetals and chemistry on polymeric support.