IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Solid-supported cross-metathesis and a formal alkane metathesis for the generation of biologically relevant molecules
Autor/es:
MENDEZ, LUCIANA; MATA, ERNESTO G
Revista:
ACS Combinatorial Science
Editorial:
AMER CHEMICAL SOC
Referencias:
Lugar: Washington; Año: 2015 vol. 17 p. 81 - 86
ISSN:
2156-8952
Resumen:
Solid-phase synthetic strategies towards the generation of libraries of biologically relevant molecules were developed using olefin cross-metathesis as a key step. It is remarkably the formal alkane metathesis based on a one-pot, microwave-assisted, ruthenium catalyzed cross-metathesis and reduction to obtain Csp3-Csp3 linkages
