IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Potential antitumoral properties of a new copper complex with santonic acid
Autor/es:
P. A. M. WILLIAMS, J. ZINCZUK, D. A. BARRIO, O. E. PIRO, O. R. NASCIMENTO,AND S. B. ETCHEVERRY
Revista:
BIOORGANIC & MEDICINAL CHEMISTRY.
Editorial:
Pergamon
Referencias:
Lugar: Oxford; Año: 2008 vol. 16 p. 4313 - 4322
ISSN:
0968-0896
Resumen:
A new copper(II) complex of santonic acid [Cu2(sant)4(H2O)2]Æ212H2O has been prepared and characterized by electronic,vibrational, EPR spectral studies, and stability determinations in solution. The presence of two antiferrromagnetically coupled coppercenters in the solid state was detected by EPR. The dinuclear Cu(II) complex crystallizes in the tetragonal P43212 space group,with a = b = 14.498(3), c = 64.07(1) A ˚ . Biological studies indicate that the complex displays interesting potential antitumoralactions.
