IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Synthesis of the carbon framework of the stephaoxocanes employing a sequential RCM/Pomeranz-Fritsch approach
Autor/es:
BRACCA, ANDREA B. J.; KAUFMAN, TEODORO S.
Revista:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY
Editorial:
Wiley-VCH Verlag GmbH and Co. KGaA
Referencias:
Año: 2007 vol. 2007 p. 5284 - 5293
ISSN:
1434-193X
Resumen:
The syntheses of two cyclodeca[ij] isoquinoline derivatives, which embody the carbon framework of stephaoxocanidine, excentricine and the recently isolated stephalonganines A, B and C, are reported. The target tricyclic compounds were prepared from isovanillin, employing a ring closing metathesis approach towards the synthesis of a benzocyclodecane-type common intermediate; different modifications of the Pomeranz-Fritsch protocol allowed the installation of the heterocyclic ring.
