(+)-Santonide, a sesquiterpenoid enol lactone derived from Artemisia

ZINCZUK, J.; RÚVEDA, E.A.; LALANCETTE, R.A.; THOMPSON, H.W.

Acta Crystallographica Section E Structure Reports

Año: 2007 vol. E63 p. 1490 - 1491

The title compound, (1R,3aS,6aS,9S)-(+)-,3a,7-trimethyl-5-oxo-1,4-ethanoperhydropentalene-1,8-carbolactone, C15H18O3, is the enol lactone of ()-isosantonic acid, and a diastereomer of (+)-parasantonide. It is a skeletally rigid tetracyclic sesquiterpene derived from ()--santonin, an anthelminthic obtained from various species of Artemisia. Molecules are linked by C—H......O close intermolecular contacts.R,3aS,6aS,9S)-(+)-,3a,7-trimethyl-5-oxo-1,4-ethanoperhydropentalene-1,8-carbolactone, C15H18O3, is the enol lactone of ()-isosantonic acid, and a diastereomer of (+)-parasantonide. It is a skeletally rigid tetracyclic sesquiterpene derived from ()--santonin, an anthelminthic obtained from various species of Artemisia. Molecules are linked by C—H......O close intermolecular contacts.