IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Facile, efficient and eco-friendly synthesis of 5-sulfenyl tetrazole derivatives of
Autor/es:
KUHN, B. L.; FORTES, M. P.; KAUFMAN, T. S.; SILVEIRA, C. C.
Revista:
TETRAHEDRON LETTERS
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdam; Año: 2014 vol. 55 p. 1648 - 1652
ISSN:
0040-4039
Resumen:
A concise, two-step eco-friendly approach towards the synthesis of 5-sulfenyl tetrazole derivatives of indoles and pyrroles, is reported. The synthesis comprises the oxone-mediated thiocyanation of the starting heterocycles towards intermediate 3-thiocyanato indoles and 2- thiocyanato pyrroles, and their subsequent treatment with sodium azide in 2-propanol:water under zinc bromide promotion.
