IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Green one-pot synthesis of 2H-pyrans under solvent-free conditions catalyzed by ethylenediammonium diacetate
Autor/es:
RIVEIRA, M. J.; MISCHNE, M. P.
Revista:
SYNTHETIC COMMUNICATIONS
Editorial:
TAYLOR & FRANCIS INC
Referencias:
Lugar: London; Año: 2013 vol. 43 p. 208 - 220
ISSN:
0039-7911
Resumen:
Ethylenediammonium diacetate readily catalyses the Knoevenagel-type condensation between 1,3-dicarbonyl substrates and alpha,beta-unsaturated aldehydes, at room temperature under solvent-free conditions. This rapid, efficient and convenient one-pot approach to the synthesis of 2H-pyrans stands as a significant advance over previously reported protocols. This environmentally friendly methodology has been successfully applied to the synthesis of biologically active natural products of interest zanthosimuline, N-methylflindersine and ferprenin.
