IQUIR 05412
INSTITUTO DE QUIMICA ROSARIO
Unidad Ejecutora - UE
artículos
Título:
Thiophenol-mediated improvement of the Pictet-Spengler cyclization of N-tosyl-Ò-phenethylamines with aldehydes
Autor/es:
CLAUDIO C., SILVEIRA; ADRIANO SIQUERIA VIEIRA; TEODORO S. KAUFMAN
Revista:
TETRAHEDRON LETTERS
Editorial:
Elsevier
Referencias:
Lugar: Amsterdam; Año: 2006 vol. 47 p. 7545 - 7549
ISSN:
0040-4039
Resumen:
The Lewis acid-catalyzed PictetSpengler condensation of N-tosyl-b-phenethylamines with aldehydes is improved by the addition of thiophenol, furnishing better yields of 1-substituted tetrahydroisoquinolines at a given time.N-tosyl-b-phenethylamines with aldehydes is improved by the addition of thiophenol, furnishing better yields of 1-substituted tetrahydroisoquinolines at a given time.
