INTEC   05402
INSTITUTO DE DESARROLLO TECNOLOGICO PARA LA INDUSTRIA QUIMICA
Unidad Ejecutora - UE
artículos
Título:
Preparation of TPP-crosslinked chitosan microparticles by spray drying for the controlled delivery of progesterone intended for estrus synchronization in cattle
Autor/es:
BUSATTO, CARLOS A.; SANTIAGO, LILIANA; FIORAMONTI, SILVANA A.; ESTENOZ, DIANA A.; HELBLING, IGNACIO M.; PESOA, JUAN I.; LUNA, JULIO A.
Revista:
PHARMACEUTICAL RESEARCH
Editorial:
SPRINGER/PLENUM PUBLISHERS
Referencias:
Lugar: New York; Año: 2018
ISSN:
0724-8741
Resumen:
Purpose Planned reproduction in cattle involves regulation ofestrous cycle and the use of artificial insemination. Cycle controlincludes the administration of exogenous progesteroneduring 5?8 days in a controlled manner allowing females tosynchronize their ovulation. Several progesterone delivery systemsare commercially available but they have several drawbacks.The aim of the present contribution was to evaluatechitosan microparticles entrapping progesterone as an alternativesystem.