Evaluation of the slip length in the slipping friction between BGE and peptides through the modeling of their CZE mobilities

DEIBER, JULIO ALCIDES; PIAGGIO, MARÍA VIRGINIA; PEIROTTI, MARTA BEATRIZ

ELECTROPHORESIS

WILEY-V C H VERLAG GMBH

Lugar: Weinheim; Año: 2013 vol. 34 p. 2648 - 2654

0173-0835

This work analyzes and discusses several physicochemical peptide chain properties that may generate partial or total BGE slip boundary conditions on the surface of peptides migrating as spherical and aspherical particles in CZE. A definition of the BGE slip length is presented which is able to account the effect of particle curvature through the associated metrical coefficients. This definition allows the distinction between partial and total BGE slip lengths. It is also shown that the BGE slip length must be variable on orthotropic aspherical particles surfaces.