INCAPE   05401
INSTITUTO DE INVESTIGACIONES EN CATALISIS Y PETROQUIMICA "ING. JOSE MIGUEL PARERA"
Unidad Ejecutora - UE
artículos
Título:
Kinetics and thermodynamics of swelling and dissolution of PVA gels obtained by freeze-thaw technique
Autor/es:
IGNACIO RINTOUL; JORGE IVÁN DAZA AGUDELO; JUAN MANUEL BADANO
Revista:
MATERIALS CHEMISTRY AND PHYSICS
Editorial:
ELSEVIER SCIENCE SA
Referencias:
Lugar: Amsterdam; Año: 2018 vol. 216 p. 14 - 21
ISSN:
0254-0584
Resumen:
p { margin-bottom: 0.25cm; direction: ltr; color: rgb(0, 0, 0); line-height: 120%; }p.western { font-family: "Calibri",sans-serif; font-size: 11pt; }p.cjk { font-family: "Calibri",sans-serif; font-size: 11pt; }p.ctl { font-family: "Times New Roman",serif; font-size: 11pt; }a:link { }PVAhydrogels obtained by freeze-thaw technique find importantapplications in regenerative medicine and controlled drug deliverytechnologies. The novelty of this contribution is the establishmentof the cross-dependency of kinetics and thermodynamics parameters ofswelling and dissolution of PVA hydrogels with the freeze-thawprocess main variables. The work also establishes cross-correlationsbetween the freeze-thaw process conditions, the gel microstructureand the properties of obtained hydrogel / hydrosoluble PVA materials.The conditions of the freeze-thaw process were selected by followingan experimental design. The time evolution of the water up-take ofPVA hydrogels was measured and used as main raw data generator. A 4-Dsurface response of the swelling and dissolution parameters in thespace of freeze-thaw process variables was obtained and analyzed interms of the resulting hydrogel and hydrosoluble polymericstructures. The 4-D surface response in the space of freeze-thawprocess variables can predict very precisely the swelling anddissolution of PVA systems and their conditions for developing fullycrosslinked hydrogel networks to fully hydrosoluble polymeric bodies.