PHOTOACOUSTIC CHARACTERIZATION OF NEW UV-MALDI MATRICES

DAVID GARA, PEDRO M.; BILMES, GABRIEL; PETROSELLI, GABRIELA; ERRA-BALSELLS, ROSA

Merida

Conferencia; 16th International Conference on Photoacoustic and Photothermal Phenomena; 2011

Ultraviolet Matrix-assisted laser desorption/ionization (UV-MALDI) is a method based on dispersing a macromolecule (analyte) in a large excess of a matrix (photosensitizer), both in solid sate. The mixture irradiated with a laser pulse is vaporized and analyte gas ions are formed and detected by mass spectrometry (MS). The mechanism of ionization during MALDI is still poorly understood and no adequate quantitative model for the complete process exists. The UV-MALDI technique involves both laser ablation and ionization of the matrix/analyte mixture after electronic excitation of the matrix.