IFLYSIB   05383
INSTITUTO DE FISICA DE LIQUIDOS Y SISTEMAS BIOLOGICOS
Unidad Ejecutora - UE
artículos
Título:
Mechanisms associated with the changes in aggregation of sodium dodecyl sulfate in urea aqueous solutions
Autor/es:
J. RAÚL GRIGERA; RICARDO YANIS ESPINOSA; C. GASTÓN FERRARA
Revista:
PROGRESS IN BIOPHYSICS AND MOLECULAR BIOLOGY
Editorial:
PERGAMON-ELSEVIER SCIENCE LTD
Referencias:
Lugar: Amsterdan; Año: 2018
ISSN:
0079-6107
Resumen:
We used simulations by Molecular Dynamics to characterize the mechanismwhereby the variations in the urea concentration modifies the micellar structure of sodium dodecyl sulfate monomers in water. From a self-assembled micellar system, we observed that increasing urea concentration leads to a decrease in aggregation number. Likewise, when increasing urea concentration, the micelles increase their nonpolar surface exposed to solvent, while the polar surface exposed to solvent decreases. This rearrangement process of SDS micelles in presence of urea is mainly due to the fact that the ions of Na + that stabilize the micellar structure increase its interaction with urea. In this process, the SDS hydrophilic head and Na + ions increases its solvation by urea, destabilizingmicellar structure and exponing the hydrophobic core to the solvent.