CINDEFI   05381
CENTRO DE INVESTIGACION Y DESARROLLO EN FERMENTACIONES INDUSTRIALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Nanomechanical properties of Bordetella pertussis depend on virulence and neighbourhood
Autor/es:
M.I. VILLALBA; O.M. YANTORNO; M.E. VELA; G.DIETLER; L.VENTURELLI; S. KASAS
Lugar:
Buenos Aires
Reunión:
Congreso; 15th Interamerican Microscopy Congress CIASEM-SAMIC; 2019
Institución organizadora:
COMITE INTERAMERICANO SOC MICROSCOPIA ELECTRONICA-CIASEM
Resumen:
Atomic force microscopy (AFM) is a widely used tool in microbiology to image and explore the nanomechanical properties of bacteria. In this work, we employed this technique to study the membrane properties of Bordetella pertussis, a Gram-negative bacterium that colonizes human airway and produces whooping cough. More specifically, we analyzed the effect of two antibiotics, erythromycin and ampicillin, on the bacterial envelope and monitored cell wall stiffness modifications during virulence changes.