CINDEFI 05381
CENTRO DE INVESTIGACION Y DESARROLLO EN FERMENTACIONES INDUSTRIALES
Unidad Ejecutora - UE
artículos
Título:
Nanomechanical Properties of Bordetella Pertussis Depend on Virulence and Neighborhood
Autor/es:
VENTURELLI, L.; KASAS, S.; VILLALBA, M.I.; YANTORNO, O.M.; VELA, M.E.; DIETLER, G.
Revista:
MICROSCOPY & MICROANALYSIS
Editorial:
CAMBRIDGE UNIV PRESS
Referencias:
Año: 2020 vol. 26 p. 125 - 126
ISSN:
1431-9276
Resumen:
Atomic force microscopy (AFM) is a widely used tool in microbiology to image and explore the nanomechanical properties of bacteria.1,2 In this work, we employed this technique to study the membrane properties of Bordetella pertussis, a Gram-negative bacterium that colonizes human airway and produces whooping cough. More specifically, we analyzed the effect of two antibiotics, erythromycin and ampicillin, on the bacterial envelope and monitored cell wall stiffness modifications during virulence changes.
