CONICET | Buscador de Institutos y Recursos Humanos

Abstract: OCCURRENCE OF MICROCYSTIS AERUGINOSA AND MICROCYSTINS IN RIO DE LA PLATA RIVER (ARGENTINA). Dar¨ªo Andrinolo; Paulo Pereira; Leda Giannuzzi; Claudia Aura; Silvia Massera; Mariela Caneo; Josep Caixach; M¨®nica Barco and Ricardo Echenique. Acta Toxicol. Argent. (2007) 15 (1): 13-18. This paper is the first report on microcystins producer blooms of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentMICROCYSTIS AERUGINOSA AND MICROCYSTINS IN RIO DE LA PLATA RIVER (ARGENTINA). Dar¨ªo Andrinolo; Paulo Pereira; Leda Giannuzzi; Claudia Aura; Silvia Massera; Mariela Caneo; Josep Caixach; M¨®nica Barco and Ricardo Echenique. Acta Toxicol. Argent. (2007) 15 (1): 13-18. This paper is the first report on microcystins producer blooms of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentDar¨ªo Andrinolo; Paulo Pereira; Leda Giannuzzi; Claudia Aura; Silvia Massera; Mariela Caneo; Josep Caixach; M¨®nica Barco and Ricardo Echenique. Acta Toxicol. Argent. (2007) 15 (1): 13-18. This paper is the first report on microcystins producer blooms of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentActa Toxicol. Argent. (2007) 15 (1): 13-18. This paper is the first report on microcystins producer blooms of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentMicrocystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata river, the most important drinking water supply of Argentina. The distribution of toxic cyanobacterium Microcystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentMicrocystis cf. aeruginosa blooms in the Argentinean coast of the Rio de la Plata river was studied from December 2003 and January 2006. Microcystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentMicrocystis aeruginosa persisted in the river with values ranged between 0 - 7.8 104 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessment4 cells ml-1. Samples of two Microcystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentMicrocystis aeruginosa water blooms were collected at La Plata river and were analyzed by the mouse bioassay and by high-performance liquid chromatography with Diode-array and MS detector. The samples showed high hepatotoxicity in mouse bioassay and, in accordance, important amount of microcystins. The bloom samples contained microcystins LR and a variant of microcystin with a molecular ion [M+H]+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessment+= 1037.8 m/z as major components. The total toxin content found in these samples was 0.94¦Ìg/mg and 0.69¦Ìg/mg of lyophilised cells. We conclude that the presence of toxic clones of Microcystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentMicrocystis aeruginosa in the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessmentin the Argentinean coast of the R¨ªo de la Plata is an actual sanitary and environmental problem and that further studies are necessary to make the risk assessment