Production of Bone Substitutes Composites based on Biogenic Materials

C FERNÁNDEZ; A OZOLS; C MARTÍNEZ; U GILABERT ; M BATILLER ; L B GARRIDO

Buenos Aires

Congreso; VI International Conference on Science and Technology of Composite Materials; 2015

The technical feasibility of producing several biodegradable biocomposites (BCO), destined to bone reconstruction or regeneration was analyzed. BCO are intended for orthopaedic, maxillofacial, plastic and neurosurgeries. Used raw materials are mostly natural materials (biogenic), abundant, renewable, and of relatively low cost, compared to commercial products.BCO are composed by inorganic and organic phases. Inorganic phases were based on natural hydroxyapatite and nacre, obtained by thermo-chemical of bovine bone and electrochemical processing of inner layer of molluscs shells, respectively.Organic phase was mainly composed by collagen, poly-`peptides, regeneration tissue macro-molecules extracted from Wharton´s jelly by physico-chemical treatment of embryonic tissues. The BCO were produced by blending organic matrix solutions with inorganic particles, which played an active role in bone regeneration, assessed by in vivo tests in rats.