Comparison of Y-chromosome haplogroup frequencies in eight Provinces of Argentina

RAMALLO V; MUCCI JM; GARCÍA A; MUZZIO M; MOTTI JMB; SANTOS MR; PÉREZ ME; ALFARO EL; DIPIERRI J,; DEMARCHI DA; BRAVI CM; BAILLIET G

Buenos Aires

Congreso; 23 rd World Congress International Society for Forensic Genetics; 2009

International Society for Forensic Genetics

Introduction and objectives: Y-chromosome haplogroups constructed from SNP markers of Y-specific regions have been largely used in population gentics trials. These data might be agood way of approximation for forensic studies on human populations showing multiethnicadmixture. In Argentina, massive migration events occurred during XIX and XX centuries.Haplogroups evidenced differential ethnic components: Native American, European, orAfrican. The objective of the present report was to analyze haplogroup frequencies in threeArgentine geographic regions: Cuyo, Center and Northwest. Materials and methods: We analyzed 778 male samples from voluntary donors from 21 dities in 8 provinces fror 17 Y-SNP by PCR-RFLP. Arlequin, Passage and NTSYS softwares were used for population analyses. Results and discussion: Nine haplogroups were identified. Q1a3a*, the major haplogroup inNative American populations was the most frequent in Northwest area (NW) (31,8%, N=507) and infrequent in the Center (C) (6%, N=109). Population comparison of haplogroup of haplogroup distribution among populations evidenced close similarity among NW populations, and high degree of differentiation on NW with the rest of the regions, Center and Cuyo. Genetic structure was analyzed using AMOVA test which showed 87,43% intrapopilation genetic variation. Fst was 0.12. A significant differentiation among groups was observed in relation with geographic distribution (0.35, P=0.001)