IMBICE   05372
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA CELULAR
Unidad Ejecutora - UE
artículos
Título:
Software Haplogroup Predictions: a word of caution
Autor/es:
MARINA MUZZIO; VIRGINIA RAMALLO; JOSEFINA M. B. MOTTI; MARIA R. SANTOS; JORGE S. LÓPEZ CAMELO; GRACIELA BAILLIET
Revista:
INTERNATIONAL JOURNAL OF LEGAL MEDICINE.
Editorial:
Springer Berlin / Heidelberg
Referencias:
Año: 2009 p. 1 - 2
ISSN:
0937-9827
Resumen:
Abstract The development of online software designed for genetic studies has been exponentially growing, providing numerous benefits to the scientific community.  However, they should be used with care, since some require adjustments. The efficiency of two programs for haplogroup prediction was tested with 119 samples of known haplotypes and haplogroups from Argentine populations. Quantitative estimates of the predictive quality of both softwares were computed with the uncertainty coefficient; and sensitivity, specificity, positive and negative likelihood ratios were also calculated to assert the reliability of both programs, showing high probabilities of assigning an incorrect haplogroup.