IMBICE 05372
INSTITUTO MULTIDISCIPLINARIO DE BIOLOGIA CELULAR
Unidad Ejecutora - UE
artículos
Título:
Software Haplogroup Predictions: a word of caution
Autor/es:
MUZZIO MARINA; RAMALLO V; MOTTI JMB; SANTOS MR; LÓPEZ CAMELO JS; BAILLIET G
Revista:
INTERNATIONAL JOURNAL OF LEGAL MEDICINE.
Editorial:
Springer
Referencias:
Año: 2010 vol. 10 p. 404 - 409
ISSN:
0937-9827
Resumen:
ESTE TRABAJO CORRESPONDE AL CAMPO DISCIPLINAR DE LA ANTROPOLOGÍA FÍSICA (DISCIPLINA DESAGREGADA 5701-ANTROPOLOGÍA FÍSICA), QUE NO SE ENCUENTRA ENTRE LAS OPCIONES A ELEGIR EN LA PLANILLA DE "CAMPO DISCIPLINAR DE LA PUBLICACIÓN". ADEMÁS, INCLUYE INFORMACIÓN SUPLEMENTARIA NO CONTABILIZADA EN EL NÚMERO DE PÁGINAS, DISPONIBLE ONLINE EN LA PÁGINA DE LA REVISTA.The development of online software designed for genetic studies has been exponentially growing, providing numerous benefits to the scientific community. However, they should be used with care, since some require adjustments. The efficiency of two programs for haplogroup prediction was tested with 119 samples of known haplotypes and haplogroups from Argentine populations. Quantitative estimates of the predictive quality of both softwares were computed with the uncertainty coefficient; and sensitivity, specificity, positive and negative likelihood ratios were also calculated to assert the reliability of both programs, showing high probabilities of assigning an incorrect haplogroup.
