IMEX   05356
INSTITUTO DE MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
THYMIC STROMAL LYMPHOPOIETIN (TSLP) IS A NEUTROPHIL CELLS MODULATOR: RELEVANCE IN THE PATHOGENESIS OF BRAIN TUMORS
Autor/es:
ITURRIZAGA J; VERMEULEN M; RABADÁN A; INFANTE A; CANDOLFI, MARIANELA; REMES LENICOV; CORONEL VALENTÍN; JANCIC C; VILLAVERDE M; GABRIELA SALAMONE
Lugar:
VIRTUAL
Reunión:
Congreso; Reunion de Sociedades de Biociencias 2020 (SAI-SAIC-SAFIS); 2020
Institución organizadora:
SAI,SAIC,SAFIS
Resumen:
Glioblastoma (GBM) is the most devastating brain tumor,with an associated poor prognosis. Despite the advances insurgery and chemoradiation, the survival of GBM patients has notimproved significantly in the past three decades. Thymic stromallymphopoietin (TSLP) is a cytokine produced primarily by activatedepithelial cells and it has been shown to be a key factor in maintainingimmune homeostasis and regulating inflammatory responses atmucosal barriers. However, recent studies have found an expandingrole for TSLP in inflammatory diseases and cancer.