Adrenal steroids modulate the immune response during Brucella abortus infection

M. VIRGINA GENTILINI; LIS N. VELASQUEZ; PAULA BARRIONUEVO; P. CONSTANZA ARRIOLA BENÍTEZ; GUILLERMO H. GIAMBARTOLOMEI; M. VICTORIA DELPINO

Mar del Plata

Congreso; LIX Reunión Científica Anual de la Sociedad Argentina de Investigación Clínica, LXII Reunión Científica Anual de la Sociedad Argentina de Inmunología; 2014

Sociedad Argentina de Investigación Clínica y Sociedad Argentina de Inmunología

Brucella abortus (Ba) induces an inflammatory response that could stimulate the endocrine system resulting in the secretion of glucocorticoids and dehydroepiandrosterone (DHEA). Our aim was to evaluate the role of adrenal hormones on the immune response in brucellosis. We found an increased in the cortisol/DHEA ratio in sera from brucellosis patients (p