IMEX   05356
INSTITUTO DE MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
artículos
Título:
Leishmania infantum and Human Visceral Leishmaniasis, Argentina
Autor/es:
BARRIO AB; PARODI C; LOCATELLI FM; MORA MC; BASOMBRÍO MA; KORENAGA M; HASHIGUCHI Y; GARCIA BUSTOS MF; GENTILE AG; MARCO JD
Revista:
EMERGING INFECTIOUS DISEASES
Editorial:
CENTERS DISEASE CONTROL
Referencias:
Año: 2012 p. 354 - 355
ISSN:
1080-6040
Resumen:
To the Editor: In Argentina,14 autochthonous human cases ofvisceral leishmaniasis (VL) werereported during 1925?1989. Thesecases occurred in different localitiesin Salta, Jujuy, Santiago del Estero,and Chaco Provinces of northwesternArgentina (online Appendix Figure,wwwnc.cdc.gov/EID/article/18/2/11-0924-FA1.htm), where cutaneousleishmaniasis (CL) caused principallyby Leishmania (Viannia) braziliensisis endemic.It had been postulated thatscattered/sporadic VL cases couldbe caused by visceralization ofdermatrophic Leishmania spp. becauseof 1) absence of already recognized L.(Leishmania) infantum vector species;2) geographic overlap with the regionwhere CL is endemic; 3) simultaneoussymptoms of CL; or 4) lack ofdetailed parasitic characterizationat the molecular level for cases ofsuspected VL (1). However, duringrecent decades, urban outbreaks ofVL have spread to southern regions ofSouth America (Mato Grosso do Sul,Brazil, and Asunción, Paraguay) nearthe northern border with Argentina.In May 2006, an autochthonoushuman case of VL was reported inPosadas (northeastern Argentina); itwas associated with the canine visceralform of the disease. In addition, thepresence of Lutzomyia longipalpissandfl ies was also reported (2).Currently, 58 human VL cases havebeen reported in Posadas (3), and>7,000 infected dogs, Lu. longipalpissandfl ies, and canine VL have beenfound 350 km south of Posadas (4).