Effects of a high-fat diet on male fertility in high fertility performance mice

RAINERO CÁCERES T; DALTON N; COHEN DJ; GIACCAGLI M; CUASNICU PS; GOMEZ ELÍAS M; DE SIERVI A; DA ROS VG

Buenos Aires

Jornada; XX Jornadas Anuales de la Sociedad Argentina de Biología.; 2018

Sociedad Argentina de Biología

The metabolic syndrome (MeS) is defined as an increase in 3 of the following factors: visceral adiposity, triglycerides, cholesterol, fasting glucose and blood pressure. Considering the worldwide rise in the prevalence of this syndrome during the last years, the aim of this study was to evaluate MeS effects on male fertility in mice with high reproductive performance. For this purpose, three-week-old hybrid (C57BL/6xBALB/c) F1 male mice received ad libitum a control diet (CD, 6% fat) or a high-fat diet (HFD, 30% fat) for 19 weeks. HFD mice ingested a higher amount of fat than CD mice (0.970.04 vs 0.250.01 g of fat/day, n=9, p