IBYME   02675
INSTITUTO DE BIOLOGIA Y MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Neural activation of the amphibans telencephalon during a passive avoidance task
Autor/es:
PUDDINGTON, MARTIN MIGUEL; PAPINI, MAURICIO; MUZIO, RUBÉN NÉSTOR
Reunión:
Otro; Behavioural Brain Research; 2014
Resumen:
Few publications exists about amphibians aversive conditioning and none of them explore its neural basis. Although at least three independent groups have determined that the ventral lateral portion of the medial telencephalon is homologous to the amygdaline complex of mammals, its function remains unexplored. In the first experiment a groups of 20 toads were assigned to an Experimental or a Control Group, and trained in a passive avoidance paradigm. All animals were placed in the illuminated compartment of a shuttle box. When subjects moved to the dark compartment a hypertonic saline solution (Experimental Group) or a less concentrated saline solution (Control Group) was delivered. Over 10 trials, animals in the Experimental Group significantly increased their latency of response. In the extinction phase all animals received the less concentrated solution. After 10 days of extinction, differences between groups disappeared. In the second experiment, neural activation of the telencephalon was studied with the AgNOR technic, after the acquisition phase. Animals in the experimental group showed higher activation in the Amygdala and the Striatum but not in the Septum and in the Medial Pallium. These results are coherent with a functional concordance hypothesis of the amphibians and the mammalian amygdala.