IBYME 02675
INSTITUTO DE BIOLOGIA Y MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Successive negative contrast in rats. Effects of frontal cortex lesions.
Autor/es:
PESZANO, V. N. & MUZIO, R. N.
Lugar:
Huerta Grande, Córdoba
Reunión:
Congreso; II Reunión Conjunta del Taller Argentino de Neurociencias y la Sociedad Argentina de Investigación en Neurociencias (SAN).; 2010
Institución organizadora:
Taller Argentino de Neurociencias y la Sociedad Argentina de Investigación en Neurociencias (SAN).
Resumen:
When
animals trained to received a reward have a surprising decrease in the quality
or magnitude of this reinforcement, instead of adjusting its performance to
that of animals always receive a small reward, show a much greater decreasing
in performance, phenomenon called Successive Negative Contrast (SNC). SNC has
been found both in consummatory (cSNC) as in instrumental (iSNC) procedures,
and the existence of different neural substrates has been postulated. It has
been shown that lesions in the limbic system have different effects on the cSNC
and iSNC, but the evidence is controversial. The frontal cortex (FC) is a
phylogenetically novel area in vertebrates, and potentially also might be
involved in the SNC (since this phenomenon is observed only in mammals). By
performing different chemical lesions in FC with quinolinic acid we evaluate
the role of this area in the SNC. In this work we present the results of
ongoing experiments, including evidence of cSNC and iSNC, and the preliminary
results of the effect of lesions of the FC on the iSNC.
