Mechanisms involved in mammalian gamete interaction

COHEN DJ; WEIGEL MUÑOZ M; CUASNICU PS; DA ROS V

Encyclopedia of Reproduction, Second Edition

Elsevier ltd

Año: 2018; p. 279 - 283

Fertilization in mammals is a complex process involving a series of coordinated steps in whichspermatozoa need to penetrate the coats that surround the ovulated egg(i.e. cumulus oophorus and zona pellucida) to then fuse with the egg plasmamembrane. This chapter will describe the unique features of the eutherianmammalian gametes as well as the strategies and molecular mechanisms involvedin each of the stages of the fertilization process.