IBYME 02675
INSTITUTO DE BIOLOGIA Y MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
artículos
Título:
Spinal cord injury drives chronic brain changes
Autor/es:
LABOMBARDA, FLORENCIA; JURE, IGNACIO
Revista:
NEURAL REGENERATION RESEARCH
Editorial:
SHENYANG EDITORIAL DEPT NEURAL REGENERATION RES
Referencias:
Año: 2017 vol. 12 p. 1044 - 1047
ISSN:
1673-5374
Resumen:
Only a few studies have considered changes in brain structures other than sensory and motor cortex after spinal cord injury, although cognitive impairments have been reported in these patients. Spinal cord injury results in chronic brain neuroinflammation with consequent neurodegeneration and cognitive decline in rodents. Regarding the hippocampus, neurogenesis is reduced and reactive gliosis increased. These longterm abnormalities could explain behavioral impairments exhibited in humans patients suffering from spinal cord trauma.
