Incidence of sperm surface autoantibodies and relationship with routine semen parameters and sperm kinematics

VERÓN GUSTAVO L; ESTOFAN ; MOLINA RI; MARIN BRIGGILER, CI; TISSERA AD; VAZQUEZ LEVIN, M

AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY

WILEY-BLACKWELL PUBLISHING, INC

Lugar: Londres; Año: 2016 vol. 76 p. 59 - 69

1046-7408

Incidence of sperm surface autoantibodies and relationship with routine semen parameters and sperm kinematics. Verón GL, Molina RI, Tissera AD, Estofan GM, Marín Briggiler CI*, Vazquez-Levin MH*. (*IGUAL CONTRIBUCION). ABSTRACT PROBLEM: AntiSperm Antibodies (ASA) are associated with male subfertility. However, results on sperm surface-bound antibodies are controversial, the relationship between ASA and semen parameters (WHO 2010) is unknown, and data on ASA and sperm kinematics are scarce. METHOD OF STUDY: A retrospective study done in men undergoing routine semen analysis (WHO 2010), ASA evaluation (direct SpermMARTM (IgG) Test) and Computer-Assisted Sperm Analysis (CASA).RESULTS: A 2.6% and a 5.9% incidence of ASA-positive cases was found (cut-off 50% and 10%, respectively; n=7492). ASA-positive samples had lower (P