IBYME 02675
INSTITUTO DE BIOLOGIA Y MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
artículos
Título:
DRIVING CARS INTO SWEET ROADS: TARGETING GLYCOSYLATED ANTIGENS IN CANCER
Autor/es:
GABRIEL RABINOVICH; ADA BLIDNER; KARINA MARIÑO
Revista:
IMMUNITY
Editorial:
CELL PRESS
Referencias:
Lugar: United States; Año: 2016
ISSN:
1074-7613
Resumen:
Engineering T cells with chimeric antigen receptors (CARs) has demonstrated remarkable success in eradicatinghematological malignancies. In this issue of Immunity, June and colleagues demonstrate the broadantitumor efficacy of a newly-designed CAR targeting the O-linked hypoglycosylated epitopes Tn andsialyl-Tn on cancer-associated MUC-1.
