IBYME 02675
INSTITUTO DE BIOLOGIA Y MEDICINA EXPERIMENTAL
Unidad Ejecutora - UE
artículos
Título:
Recombinant human zona pellucida protein C produced in Chinese hamster ovary (CHO) cells binds to human spermatozoa and inhibits sperm-zona pellucida interaction
Autor/es:
MARÍN BRIGGILER CI; GONZALEZ ECHEVERRÍA MF; HARRIS JD; VAZQUEZ-LEVIN MH
Revista:
FERTILITY AND STERILITY
Editorial:
Elsevier
Referencias:
Año: 2007
ISSN:
0015-0282
Resumen:
Recombinant human zona pellucida protein C (rec-hZPC) expressed in Chinese hamster ovary (CHO) cells associates to the acrosomal region of human spermatozoa, and inhibits sperm-ZP interaction in the Hemizona assay. Rec-hZPC may be a useful tool towards the development of diagnostic methods for male infertility and the elucidation of the molecular basis of fertilization.
