IAM   02674
INSTITUTO ARGENTINO DE MATEMATICA ALBERTO CALDERON
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Left Ventricular Hypertrophy: An allometric comparative analysis of different ECG markers
Autor/es:
MP BONOMINI; F INGALLINA; V BARONE; ME VALENTINUZZI; PD ARINI
Lugar:
Mar del Plata
Reunión:
Congreso; XVIII Congreso Argentino de Bioingeniería y VII Jornadas de Ingeniería Clínica, SABI 2011; 2011
Institución organizadora:
Soc. Argentina de Bioingeniería
Resumen:
Abstract. Allometry, in general biology, measures the relative growth of a part in relation to
the whole living organism. Left ventricular hypertrophy (LVH) is the heart adaptation to
excessive load (systolic or diastolic). The increase in left ventricular mass leads to an increase
in the electrocardiographic voltages. Based on clinical data, we compared the allometric
behavior of three different ECG markers of LVH. To do this, the allometric fit AECG = d + b
(VM) relating left ventricular mass (estimated from ecocardiographic data) and ECG
amplitudes (expressed as the Cornell-Voltage, Sokolow and the ECG overall voltage indexes)
were compared. Besides, sensitivity and specifity for each index were analyzed. The more
sensitive the ECG criteria, the better the allometric fit. In conclusion: The allometric paradigm
should be regarded as the way to design new and more sensitive ECG-based LVH markers.