Study of T-wave morphology parameters based on Principal Components Analysis during acute myocardial ischemia

FABRICIO HUGO BAGLIVO; PEDRO DAVID ARINI

Mar del Plata

Congreso; XVIII Congreso Argentino de Bioingeniería y VII Jornadas de Ingeniería Clínica, SABI 2011; 2011

Sociedad Argentina de Ingeniería Biomédica

Abstract. Electrocardiographic repolarization abnormalities can be detected by Principal Components Analysis of the T-wave. In this work we studied the effect of signal averaging on the mean value and reproducibility of the ratio of the 2nd to the 1st eigenvalue of T-wave (T21) and the absolute and relative T-wave residuum (ATWR) and (RTWR) in the ECG during ischemia induced by Percutaneous Coronary Intervention. Also, the intra-subject and inter-subject variability of T-wave parameters have been analyzed. Results showed that ATWR and RTWR  evaluated from the average of 10 complexes had lower values and higher reproducibility than those obtained from 1 complex. On the other hand T21 calculated from 10 complexes did not show statistical differences versus the T21 calculated on single beats. The results of this study corroborate that, with a signal averaging technique, the 2nd and the 1st eigenvalue are not affected by noise while the 4th to 8th eigenvalues are so much affected by this, suggesting the use of the signal averaged technique before calculation of absolute and relative T-wave residuum. Finally, we have shown that T-wave morphology parameters present high intra-subject stability.