Visual input plays a key role in the retinal protection induced by enriched environment against acute retinal ischemia

DORFMAN D; DIEGUEZ HH; ARANDA ML; KELLER SARMIENTO MI; GONZÁLEZ FLEITAS MF; ROSENSTEIN RE

Seattle

Congreso; ARVO Annual Meeteng 2016; 2016

Association For Research In Vision And Ophthalmology

Purpose:Enriched environment (EE) constitutes a strategy that boosts locomotor, exploratory, visual, and cognitive activities, as well as social interaction and voluntary physical exercise. Ischemia is a key component of several retinal diseases that are leading causes of irreversible blindness. We have shown that the exposure to EE protects the retina against acute unilateral ischemia in adult rats. In this work, we analysed the involvement of visual processing in the protection induced by EE against retinal ischemic damage.