CEFYBO 02669
CENTRO DE ESTUDIOS FARMACOLOGICOS Y BOTANICOS
Unidad Ejecutora - UE
artículos
Título:
TPRV-1 expression in human preeclamptic placenta.
Autor/es:
ABAN C; FARINA MG ; LEGUIZAMON GF; MARTINEZ N; DAMIANO AE
Revista:
PLACENTA
Editorial:
W B SAUNDERS CO LTD
Referencias:
Lugar: Londres; Año: 2016 vol. 40 p. 25 - 28
ISSN:
0143-4004
Resumen:
Preeclampsia is a multisystem disorder unique to human pregnancy, characterized by abnormal placentation. Although its causes remain unclear, it is known that the expression of several transporters is altered. Transient receptor potential vanilloid 1 (TRPV-1) is a non-selective cation channel, present in human placenta. Here, we evaluated the expression of TRPV-1 in preeclamptic placentas. We observed a deregulation in TRPV-1 expression in these placentas which may explain the impaired Ca2+ homeostasis found in preeclampsia.
