INGEBI   02650
INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR "DR. HECTOR N TORRES"
Unidad Ejecutora - UE
artículos
Título:
Molecular diagnosis and treatment monitoring of congenital transmission of Trypanosoma cruzi to twins of a triplet delivery
Autor/es:
BURGOS JM; ALTCHEH J; PETRUCELLI N; BISIO M; LEVIN MJ; FREILIJ H; SCHIJMAN AG
Revista:
DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASES
Editorial:
Elsevier Biomedical
Referencias:
Año: 2009 vol. 65 p. 58 - 61
ISSN:
0732-8893
Resumen:
Congenital transmission of Trypanosoma cruzi was diagnosed in 2 triplets born to a triamniotic bichorionic delivery. Only the sisters sharing the placenta became infected, as diagnosed by microhematocrit and/or polymerase chain reaction of 3 parasite targets. The neonates´ parasitologic response to benznidazole was monitored. Molecular strategies allowed genotyping lineage IId and identical minicircle signatures in both triplets, showing they harbored the same maternal parasite populations.