INGEBI   02650
INSTITUTO DE INVESTIGACIONES EN INGENIERIA GENETICA Y BIOLOGIA MOLECULAR "DR. HECTOR N TORRES"
Unidad Ejecutora - UE
artículos
Título:
The smoking gun in nicotine-induced anorexia.
Autor/es:
RUBINSTEIN M, LOW MJ
Revista:
CELL METABOLISM
Editorial:
CELL PRESS
Referencias:
Lugar: United States; Año: 2011 vol. 14 p. 145 - 147
ISSN:
1550-4131
Resumen:
Hypothalamic pro-opiomelanocortin (POMC) neurons are the major source of anorectic melanocortin peptides in the brain. A recent study (Mineur et al., 2011) demonstrates that nicotine directly stimulates arcuate POMC neurons through nicotinic acetylcholinergic á3â4 receptors, suggesting a new mechanism to understand the inverse relationship between tobacco smoking and body weight.