FERNÁNDEZ, ARIEL

Glycosylation of SARS-CoV-2 Steers Evolutionary Outcomes in the Postvaccination Phase

ACS Pharmacology and Translational Science; Año: 2021 vol. 4 p. 410 - 412

FERNÁNDEZ, ARIEL

COVID-19 Evolution in the Post-Vaccination Phase: Endemic or Extinct?

ACS Pharmacology and Translational Science; Año: 2021 vol. 4 p. 403 - 405

FERNÁNDEZ, ARIEL

Toward the Next-Generation COVID-19 Vaccines That Circumvent Antigenic Drift while Defusing Viral Infection

ACS Pharmacology and Translational Science; Año: 2021 vol. 4 p. 1018 - 1020

FERNÁNDEZ, ARIEL

Artificial Intelligence Deconstructs Drug Targeting in Vivo by Leveraging a Transformer Platform

ACS Medicinal Chemistry Letters; Año: 2021 vol. 12 p. 1052 - 1055

FERNÁNDEZ, ARIEL

Artificial Intelligence Set to Reverse Engineer Drug Targeting in the Cell

ACS Pharmacology and Translational Science; Año: 2021 vol. 4 p. 1256 - 1259

ARIEL FERNANDEZ STIGLIANO

Editorial: Alternative antigen to defuse SARS-CoV-2 delta variant and its ensuing evolutionary lineage

EXPERT OPINION ON THERAPEUTIC TARGETS; Lugar: London; Año: 2021 vol. 25 p. 913 - 915

FERNÁNDEZ, ARIEL

SARS-CoV-2 Glycosylation Suggests That Vaccines Should Have Adopted the S1 Subunit as Antigen

ACS Pharmacology and Translational Science; Año: 2021 vol. 4 p. 1016 - 1017

FERNÁNDEZ, ARIEL

Artificial Intelligence Teaches Drugs to Target Proteins by Tackling the Induced Folding Problem

MOLECULAR PHARMACEUTICS; Año: 2020 vol. 17 p. 2761 - 2767

FERNÁNDEZ, ARIEL

Deep Learning Unravels a Dynamic Hierarchy While Empowering Molecular Dynamics Simulations

ANNALEN DER PHYSIK; Año: 2020 vol. 532

FERNÁNDEZ, ARIEL

Structural Impact of Mutation D614G in SARS-CoV-2 Spike Protein: Enhanced Infectivity and Therapeutic Opportunity

ACS Medicinal Chemistry Letters; Año: 2020 vol. 11 p. 1667 - 1670

INDA, MARÍA EUGENIA; ALMADA, JUAN CRUZ; VAZQUEZ, DANIELA BELÉN; BORTOLOTTI, ANA; FERNÁNDEZ, ARIEL; RUYSSCHAERT, JEAN MARIE; CYBULSKI, LARISA ESTEFANÍA

Driving the catalytic activity of a transmembrane thermosensor kinase

CELL. MOLEC. LIFE SCIEN.; Año: 2020 vol. 77 p. 3905 - 3912

FERNÁNDEZ, ARIEL

Artificial Intelligence Steering Molecular Therapy in the Absence of Information on Target Structure and Regulation

JOURNAL OF CHEMICAL INFORMATION AND MODELING; Año: 2020 vol. 60 p. 460 - 466

ARIEL FERNANDEZ

Defusing SARS-CoV-2: Emergency Brakes in a Vaccine Failure Scenario

ACS Pharmacology & Translational Science; Año: 2020 vol. 3 p. 1425 - 1426

FERNÁNDEZ, ARIEL

Protein structural defects enable pharmaceutical targeting while functionalizing the M2 proton channel

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS; Año: 2019 vol. 514 p. 86 - 91

FERNÁNDEZ, A.

Deep Learning to Therapeutically Target Unreported Complexes

TRENDS IN PHARMACOLOGICAL SCIENCES; Año: 2019 vol. 40 p. 551 - 554

INDA, MARÍA EUGENIA; VAZQUEZ, DANIELA B.; FERNÁNDEZ, ARIEL; CYBULSKI, LARISA E.

Reverse Engineering of a Thermosensing Regulator Switch

JOURNAL OF MOLECULAR BIOLOGY; Año: 2019 vol. 431 p. 1016 - 1024

FERNÁNDEZ, ARIEL

Manfred Eigen

PHYSICS TODAY; Año: 2019 vol. 72 p. 67 - 67

FERNÁNDEZ, ARIEL

Drug-based cancer therapy to overcome immune resistance by steering tumor evolution

EXPERT OPINION ON DRUG DISCOVERY; Año: 2019 vol. 14 p. 5 - 8

FERNÁNDEZ, ARIEL

Targeted therapy to annihilate the immune-evading phenotype in cancer evolution

EXPERT OPINION ON THERAPEUTIC TARGETS; Año: 2018 vol. 22 p. 559 - 562

FERNÁNDEZ, ARIEL

Stickiness of the Hydrogen Bond

ANNALEN DER PHYSIK; Año: 2018 vol. 530 p. 1800162 - 1800162

FERNÁNDEZ, ARIEL

Engineering Tumor Hypersusceptibility to Checkpoint Immunotherapy

Trends in Cancer; Lugar: Cambridge, Massachusetts; Año: 2017 vol. 3 p. 675 - 677

FERNÁNDEZ, ARIEL

Making Targeted Therapy Compatible with Checkpoint Immunotherapy

TRENDS IN BIOTECHNOLOGY; Año: 2017 vol. 35 p. 582 - 584

FERNÁNDEZ, ARIEL

Dielectric response of frustrated water down to a single-molecule contribution

ANNALEN DER PHYSIK; Año: 2017 vol. 529 p. 1600373 - 1600373

ARIEL FERNANDEZ; RIDGWAY SCOTT

Advanced modeling reconciles counterintuitive decisions in lead optimization

TRENDS IN BIOTECHNOLOGY; Lugar: Londres; Año: 2017 vol. 30 p. 490 - 497

ARIEL FERNANDEZ; RIDGWAY SCOTT

Drug leads for interactive protein targets with unknown structure

DRUG DISCOVERY TODAY; Lugar: Amsterdam; Año: 2016 vol. 21 p. 531 - 535

ARIEL FERNANDEZ

Acid-base chemistry of frustrated water at protein interfaces

FEBS LETTERS; Lugar: Amsterdam; Año: 2016 vol. 590 p. 215 - 223

ARIEL FERNANDEZ

Non-Debye frustrated hydration steers biomolecular association: interfacial tension for the drug designer

FEBS LETTERS; Lugar: Amsterdam; Año: 2016 vol. 590 p. 3481 - 3491

ARIEL FERNANDEZ

Packing defects functionalize soluble proteins

FEBS LETTERS; Lugar: Amsterdam; Año: 2015 vol. 589 p. 967 - 973

ARIEL FERNANDEZ

Quantum theory of interfacial tension quantitatively predicts spontaneous charging of nonpolar aqueous interfaces

PHYSICS LETTERS A; Lugar: Amsterdam; Año: 2015 vol. 379 p. 2405 - 2408

MARIA EUGENIA INDA ; MICHEL VANDENBRANDEN; ARIEL FERNANDEZ ; DIEGO DE MENDOZA; JEAN-MARIE RUYSSCHAERT; LARISA ESTEFANIA CYBULSKI

A lipid-mediated conformational switch modulates the thermosensing activity of DesK

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2014 vol. 111 p. 3579 - 3584

ARIEL FERNANDEZ

Water promotes the sealing of nanoscale packing defects in folding proteins

JOURNAL OF PHYSICS CONDENSED MATTER; Lugar: Londres; Año: 2014 vol. 26 p. 202101 - 202101

ARIEL FERNANDEZ

Communication: Chemical functionality of interfacial water enveloping nanoscale structural defects in proteins

JOURNAL OF CHEMICAL PHYSICS; Lugar: New York; Año: 2014 vol. 140 p. 221102 - 221102

JOAN MONTES DE OCA; ARIEL RODRIGUEZ-FRIS; GUSTAVO APPIGNANESI; ARIEL FERNANDEZ

Productive induced metastability in allosteric modulation of kinase function

FEBS JOURNAL; Lugar: Londres; Año: 2014 vol. 281 p. 3079 - 3091

ARIEL FERNANDEZ

Synergizing immunotherapy with molecularly targeted anticancer treatment

DRUG DISCOVERY TODAY; Lugar: Amsterdam; Año: 2014 vol. 19 p. 1427 - 1432

ARIEL FERNANDEZ

Breakdown of the Debye polarization ansatz at protein-water interfaces

JOURNAL OF CHEMICAL PHYSICS; Lugar: New York; Año: 2013 vol. 138 p. 225103 - 225103

ARIEL FERNANDEZ

Supramolecular evolution of protein organization

ANNUAL REVIEW OF GENETICS; Lugar: Palo Alto, California; Año: 2013 vol. 47 p. 1 - 17

MARIA BELEN SIERRA; SEBASTIAN ACCORDINO; ARIEL RODRIGUEZ-FRIS; MARCELA MORINI; GUSTAVO APPIGNANESI; ARIEL FERNANDEZ STIGLIANO

Protein packing defects heat up interfacial water

European Physical Journal E; Año: 2013 vol. 36 p. 62 - 62

ARIEL FERNANDEZ

The principle of minimal episteric distortion of the water matrix and its role in protein folding

JOURNAL OF CHEMICAL PHYSICS; Lugar: New York; Año: 2013 vol. 139 p. 85101 - 85101

ARIEL FERNANDEZ

COMMUNICATION: Nanoscale electrostatic theory of epistructural fields at the water-protein interface

JOURNAL OF CHEMICAL PHYSICS; Lugar: New York; Año: 2012 vol. 137 p. 231101 - 231101

ARIEL FERNANDEZ; CHRISTOPHER FRASER; RIDGWAY SCOTT

Purposely engineered drug-target mismatches for entropy-based drug optimization

TRENDS IN BIOTECHNOLOGY; Lugar: Londres; Año: 2012 vol. 30 p. 1 - 7

ARIEL FERNANDEZ

Epistructural thermodynamics of soluble proteins

JOURNAL OF CHEMICAL PHYSICS; Lugar: New York; Año: 2012 vol. 136 p. 91101 - 91101

SEBASTIAN ACCORDINO; MARCELA MORINI; MARIA BELEN SIERRA; ARIEL RODRIGUEZ-FRIS; GUSTAVO APPIGNANESI; ARIEL FERNANDEZ

Wrapping mimicking in drug-like small molecules disruptive of protein-protein interfaces

PROTEINS: STRUCTURE, FUNCTION AND GENETICS; Lugar: New York; Año: 2012 vol. 80 p. 1755 - 1765

ARIEL FERNANDEZ

Epistructural tension promotes protein associations

PHYSICAL REVIEW LETTERS; Lugar: New York; Año: 2012 vol. 108 p. 188102 - 188102

SEBASTIAN ACCORDINO; ARIEL RODRIGUEZ-FRIS; GUSTAVO APPIGNANESI; ARIEL FERNANDEZ

A unifying motif of intermolecular cooperativity in protein associations

European Physical Journal E; Año: 2012 vol. 35 p. 59 - 59

ARIEL FERNANDEZ

Biology Avoids Phase Separations

Journal of Physics A: Mathematical and Theoretical; Año: 2011 p. 46468 - 46468

ARIEL FERNANDEZ; MICHAEL LYNCH

Nonadaptive origin of interactome complexity

NATURE; Lugar: Londres; Año: 2011 vol. 474 p. 502 - 505

ARIEL FERNANDEZ

Variational mechanics of water at biological interfaces

JOURNAL OF PHYSICS A-MATHEMATICAL AND THEORETICAL; Lugar: Londres; Año: 2011 vol. 44 p. 292001 - 292001

ARIEL FERNANDEZ; YUN-HUEI TZENG; SZE-BI HSU

Subfunctionalization reduces the fitness cost of gene duplication in human by buffering dosage imbalances

BMC GENOMICS; Año: 2011 vol. 12 p. 604 - 604

ARIEL FERNANDEZ; JIANPING CHEN

Human capacitance to dosage imbalance: Coping with inefficient selection

GENOME RESEARCH; Año: 2009 vol. 19 p. 2185 - 2192

ARIEL FERNANDEZ; KRISTINA ROGALE; RIDGWAY SCOTT; HAROLD SCHERAGA

Inhibitor design by wrapping packing defects in HIV-1 proteins

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2004 vol. 101 p. 11640 - 11645

ARIEL FERNANDEZ; R. STEPHEN BERRY

Molecular dimension explored in evolution to promote proteomic complexity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2004 vol. 101 p. 13460 - 13465

ARIEL FERNANDEZ

Keeping dry and crossing membranes

NATURE BIOTECHNOLOGY; Año: 2004 vol. 22 p. 1081 - 1084

ARIEL FERNANDEZ; HAROLD SCHERAGA

Insufficiently dehydrated hydrogen bonds as determinants for protein interactions

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2003 vol. 100 p. 113 - 118

ARIEL FERNANDEZ; JOZSEF KARDOS; RIDGWAY SCOTT; YUJI GOTO; R. STEPHEN BERRY

Structural defects and the diagnosis of amyloidogenic propensity

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2003 vol. 100 p. 6446 - 6451

ARIEL FERNANDEZ; RIDGWAY SCOTT

Adherence of packing defects in soluble proteins

PHYSICAL REVIEW LETTERS; Año: 2003 vol. 91 p. 18102 - 18102

ARIEL FERNANDEZ; R. STEPHEN BERRY

Proteins with hydrogen-bond packing defects are highly interactive with lipid bilayers: implications for amyloidogenesis

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Año: 2003 vol. 100 p. 2391 - 2396

ARIEL FERNANDEZ; ANDRES COLUBRI; R. STEPHEN BERRY

Topology to geometry in protein folding: beta-lactoglobulin

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA; Lugar: Washington DC, USA; Año: 2000 vol. 97 p. 14062 - 14066

ARIEL FERNANDEZ; GUSTAVO APPIGNANESI

Variational approach to relaxation in complex free energy landscapes: The polymer folding problem

PHYSICAL REVIEW LETTERS; Lugar: New York; Año: 1997 vol. 78 p. 2668 - 2672

ARIEL FERNANDEZ; HERSCHEL RABITZ

Localization of strain in the RNA backbone and its functional implication

PHYSICAL REVIEW LETTERS; Año: 1992 vol. 69 p. 546 - 549

ARIEL FERNANDEZ

Glassy kinetic barriers between conformational substates in RNA

PHYSICAL REVIEW LETTERS; Año: 1990 vol. 64 p. 2328 - 2331