INVESTIGADORES
ROSSO Osvaldo Anibal
artículos
Título:
Diabetic Erythrocytes Test by Correlation Coefficient
Autor/es:
A. M. KOROL; P. FORESTO; M. DARRIGO; O. A. ROSSO
Revista:
The Open Medical Informatics Journal
Editorial:
Bentham Science
Referencias:
Año: 2008 vol. 2 p. 105 - 111
ISSN:
1874-4311
Resumen:
Even when a healthy individual is studied, his/her erythrocytes in capillaries continually change their shape in synchronized erratic fashion. In this work, the problem of characterizing the cell behavior is studied from the perspective of bounded correlated random walk, based on the assumption that diffractometric data involves both deterministic and stochastic components. The photometric readings are obtained by ektacytometry over several millions of shear elongated cells, using a home-made device called Erythrodeformeter. We have only a scalar signal and no governing equations; therefore the complete behavior has to be reconstructed in an artificial phase space. To analyze dynamics we used the technique of time delay coordinates suggested by Takens, May algorithm, and Fourier transform. The results suggest that on random-walk approach the samples from healthy controls exhibit significant differences from those from diabetic patients and these could allow us to claim that we have linked mathematical nonlinear tools with clinical aspects of diabetic erythrocytes’ rheological properties.