IBR 13079
INSTITUTO DE BIOLOGIA MOLECULAR Y CELULAR DE ROSARIO
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
A minimal sensor that responds to membrane fluidity.
Autor/es:
LARISA E. CYBULSKI; MARIANA MARTÍN, CECILIA MANSILLA, ARIEL FERNANDEZ; AND DIEGO DE MENDOZA.
Lugar:
Carlos Paz, Noviembre 2008
Reunión:
Congreso; XLIV Reunión Anual de la Sociedad Argentina de Bioquímica y Biología Molecular (SAIB).; 2008
Institución organizadora:
Sociedad Argentina de Bioquímica y Biología Molecular (SAIB).
Resumen:
Membrane proteins have a major role in transmitting signals across membranes and are essential to communicate with the environment. In our work we focus on regulation of membrane fluidity by the molecular thermosensor DesK in Bacillus subtilis. The discovery that both sensing and transmission of DesK (which has five TMs), could be captured into one single chimerical TM segment, the so-called minimal sensor, now opens up the way to elucidate for the first time in molecular detail how transmembrane domains (TM) sense and transmit information to the transcriptional system.
