Dilucidating the role of AtUK80 in Arabidopsis thaliana

ZANOR MI; ARMAS A; BONDINO HG; VALLE EM

Congreso; SAIB 2013; 2013

The functional characterization of proteins with unknown function is one of the main challenges in modern biology. AtUK80 was identified in an activation tagging experiment performed in order to find novel oxidative stress related genes. Homologues of this gene are present in other members of the planta kingdom and in a photosynthetic member of the protist kingdom. Analysis of silenced and over expressing Arabidopsis lines revealed that this protein might be involved in the regulation of vesicular trafficking in Arabidopsis. Additionally, AtUK80 co-immunoprecipitate with the multifaceted glycolitic enzyme glyceraldhyde 3P dehydrogenasa. Taking into account that this enzyme is a key member in H2O2 signaling cascade in plants through activation of Phospholipase Dd we postulate that AtUK80 might be involved in the H2O2 signaling pathway by modulating vesicular trafficking events.