Daily rewiring of adult networks in Drosophila.

CERIANI MF

Ginebra

Conferencia; Dept. of Genetics and Evolution. University of Geneva, Switzerland. June 26th; 2015

Dept. of Genetics and Evolution. University of Geneva, Switzerland.

The long-term goal of our lab is to understand the molecular and cellular basis of behavior and how this relationship changes throughout life. Specifically, we are interested in unraveling how specific subsets of circadian pacemakers in the Drosophila brain encode ¨time of day¨ information and thus achieve coherence within the network. Through forward genetic screens we have identified not only novel neurotransmitters relevant in such communication but also retrograde signaling pathways that help establish the daily period of locomotor behavior. In addition we are exploring the contribution of the daily remodeling of axonal terminals of a specific subset of pacemaker neurons as an alternative means of transmitting time-relevant cues.