IIBBA 05544
INSTITUTO DE INVESTIGACIONES BIOQUIMICAS DE BUENOS AIRES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Conformational diversity in mono and multiple-domain proteins: Relationship with protein evolution
Autor/es:
DIEGO JAVIER ZEA; MARIA SILVINA FORNASARI; CRISTINA MARINO BUSLJE; GUSTAVO PARISI
Lugar:
Long Beach
Reunión:
Congreso; 3DSIG: Structural Bioinformatics and Computational Biophysics.; 2012
Institución organizadora:
ISCB
Resumen:
There is a negative correlation between the evolutionary rate and conformational diversity, measured as the maximum root-mean-square deviation between two conformers, for human´s mono-domain proteins but this correlation disappear in multi-domain proteins. Conformational diversity can be an important factor in the modulation of evolution at domain level.
