INTEMA   05428
INSTITUTO DE INVESTIGACIONES EN CIENCIA Y TECNOLOGIA DE MATERIALES
Unidad Ejecutora - UE
congresos y reuniones científicas
Título:
Tamoxifen-loaded PLGA nanoparticles: preparation and characterization
Autor/es:
JOSÉ KENNY; NICOLETTA RESCIGNANO; MERARI CHEVALIER; VERA ALVAREZ
Lugar:
Granada
Reunión:
Conferencia; XI Spanish-Portuguese Conference on Controlled Drug Delivery ("Revolutionary Approaches in Nanomedicine Development"); 2016
Resumen:
Depending upon the dose and the concentration Tamoxifen (TMX) has several side effects, such as endometrial carcinoma for postmenopausal women. Other side effects include liver cancer, venous thrombosis, pulmonary emboli, and an ocular effect includes retinopathy and corneal opacities. PLGA posses attractive features for drug delivery such as protection of drug from degradation, possibility of sustained release, possibility to modify surface properties to provide stealthness and/or better interaction with biological materials and possibility to target nanoparticles to specific organs or cells.