PLA/PEG-b-PLA particles: Promising peptide carrier

DANIELA GONZALEZ; MÓNICA GARCÍA; VERA ALVAREZ; MERARI CHEVALIER; ALVARO JIMENEZ KAIRUZ

Granada

Conferencia; XI Spanish-Portuguese Conference on Controlled Drug Delivery ("Revolutionary Approaches in Nanomedicine Development"); 2016

Over the past decade, significant progress has been made in the development of new pharmaceutical technology platforms based on different kind of systems. Therapeutically effective and patient-compliant drug delivery systems continuously lead researchers to design novel tools and strategies. In particular, polymeric micro and nanoparticles are micron and submicron size entities which can be made from a wide variety of natural and synthetic polymers. Due to particle?s ability to improve the efficiency of current therapeutic treatments, this type of devices are being extensively studied and used as drug carriers and controlled release systems in the field of biomaterials, medicine and pharmacy. Considering polylactic acid capability for high loading drugs and its ability to modulate drug release, this work attempts to study the physicochemical and biopharmaceutical properties of PLA/PEG-b-PLA polylisineparticulated carriers