Multiscale analyses for the mechanical characterization of trabecular bone and the design of biomimetic bone microstructures and scaffolds

A. P. CISILINO; L. COLABELLA; P. KOWALCZYK; G. HAÏAT

Buenos Aires

Workshop; Workshop on Flow of Granular Materials and Stresses under Different Solicitations; 2016

Proyecto CAFCI, Universidad Tecnológica Nacional, Regional La Plata

Bone tissue mechanical properties and trabecu- lar microarchitecture are the main factors that determine the biomechanical properties of cancellous bone. Artifi- cial cancellous microstructures, typically described by a reduced number of geometrical parameters, can be designed to obtain a mechanical behavior mimicking that of natural bone. In this work, we assess the ability of the parame- terized microstructure introduced by Kowalczyk (Comput Methods Biomech Biomed Eng 9:135?147, 2006.doi:10. 1080/10255840600751473) to mimic the elastic response of cancellous bone. Artificial microstructures are compared with actual bone samples in terms of elasticity matrices and their symmetry classes.